What is Hydrophilic Guidewire?

A hydrophilic guidewire is a thin, flexible wire used in interventional radiology and cardiology procedures to guide catheters through blood arteries. Its hydrophilic coating, which forms a slick surface when exposed to moisture (blood or salt water), is what makes it unique. The hydrophilic coating’s lubricating properties reduce friction between the guidewire and the vessel wall, facilitating easier travel and lowering the possibility of injury to the vessel during catheterization.

Composition of a Guidewire

The hydrophilic guidewire consists of two main parts:

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• Core Wire: The strength and flexibility required to manoeuvre through complex capillaries are provided by this center shaft. Common materials include:
  • Stainless Steel: Durable and reasonably priced.
  • Nitinol: An alloy with form memory renowned for its exceptional pushability, kink resistance, and flexibility.
• Hydrophilic Coating: The key to its operation is the hydrophilic coating, a specific layer put to the core wire. Hydrophilic plastics include:
  • Polytetrafluoroethylene (PTFE): A commonly used polymer renowned for having minimal friction.
  • Hydrogels: Water-absorbent polymers that form a lubricating layer when exposed to moisture.

Hydrophilic Guidewire Characteristics

• Excellent Lubricity: The hydrophilic coating provides remarkable smoothness, reducing blood vessel friction for easy travel.
• Increased Flexibility: Designed to bend and negotiate complex capillaries without kinking.
• Fluoroscopic Visibility: Good vision under fluoroscopy guidance during surgeries ensured by radiopaque markers.
• Versatility: Available in a range of lengths, diameters, and tip designs to accommodate various interventional procedures.

Applications of Guidewires

These guidewires are extremely useful in a variety of minimally invasive treatments due to their versatility:

• Cardiovascular: Treatment of heart blockages via coronary angioplasty and stenting.
• Peripheral Vascular: Treating blockages in arteries leading to the legs using angioplasty and stenting.
• Neurovascular: Handling disorders of the nervous system, including stroke.
• Gastrointestinal: Enabling procedures such as Endoscopic Retrograde Cholangiopancreatography (ERCP).
• Urological: Making the ureters accessible for different types of procedures.

Benefits of Hydrophilic Guidewires in Angioplasty

Compared to conventional guidewires, hydrophilic guidewires offer several important features that improve patient outcomes and procedure efficiency:

• Improved Trackability: The lubricating coating reduces blood vessel friction, enabling smooth navigation through convoluted paths.
• Decreased Trauma: Lower friction reduces trauma to artery walls, decreasing complications and speeding up recovery.
• Enhanced Procedural Success: Smooth navigation and reduced vascular trauma increase the success rate of interventional operations.
• Enhanced Efficiency: Shorter procedure durations, less patient discomfort, and potentially lower medical expenses.

Considerations for Guidewires

Although hydrophilic guidewires have several benefits, certain considerations ensure patient safety and optimal performance:

• Handling: Proper handling methods are essential to preserve the hydrophilic coating’s integrity.
• Catheter Compatibility: Ensuring compatibility between the guidewire and other devices used in the process is crucial.
• Catheter Selection: Choosing the right guidewire size and tip configuration for the particular surgery ensures optimal navigation and outcomes.
• Allergic Responses: Although rare, allergic responses to the components in the hydrophilic coating may occur in some individuals.

Future of Hydrophilic Guidewires

The following innovations are keeping guidewire development moving forward:

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• Enhanced Coatings: Technological advancements offer more lubrication, reducing friction and improving navigation.
• Integrated Imaging: Future versions may incorporate imaging modalities for real-time viewing during navigation.
• Patient-Specific Customization: Customized guidewires that navigate distinct vascular channels more effectively.

Hydrophilic Guidewire Safety Measures

To ensure maximum safety when using these guidewires, adhere to these important guidelines:

• Inspection: Regularly check the guidewire for damage indicators such as kinks or deterioration of the coating.
• Instructions: Follow the manufacturer’s instructions for handling, use, and compatibility with other devices.
• Disposal: Dispose of discarded guidewires according to medical waste standards to avoid contamination and environmental risks.

Hydrophilic Guidewire Training & Education

To maximize the application of these guidewires, healthcare personnel must have the appropriate training:

• Training Programs: Specific programs instruct users on how to choose guidewires, handle them safely, and use them with other interventional devices.
• Continuing Education: Regular updates on technological advancements and best practices.
• Training with Simulation: Simulation models enable hands-on practice and skill improvement using these guidewires.

Regulatory Considerations for Guidewires

Hydrophilic guidewire development and application are subject to stringent regulations:

• Manufacturing Standards: Adherence to regulatory standards such as ISO .
• Approval Procedures: New designs or revisions require approval by regulatory organizations like the FDA.
• Post-Market Surveillance: Monitoring guidewires post-market introduction to identify and resolve potential safety issues.

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Regulatory Considerations for Guidewires

Hydrophilic guidewire development and application are subject to stringent regulations:

• Manufacturing Standards: Adherence to regulatory standards such as ISO .
• Approval Procedures: New designs or revisions require approval by regulatory organizations like the FDA.
• Post-Market Surveillance: Monitoring guidewires post-market introduction to identify and resolve potential safety issues.

Hydrophilic guidewires are a major achievement in interventional medicine with significant benefits for patients and medical professionals. Our website focuses on medical devices and minimally invasive procedures. Contact us for more information on our high-quality guidewires designed to meet the unique requirements of various interventional techniques.

Cerenovus Agility 10 Steerable Guidewire Stainless steel with hydrophilic coating 0.010 195 Shapeable tip The soft tips enable easy shapeability and safe vessel access; available in standard and soft configurations Cerenovus Agility 14 Steerable Guidewire Stainless steel with hydrophilic coating 0.014 205, 350 Shapeable tip The soft tips enable easy shapeability and safe vessel access; available in standard and soft configurations Cerenovus Agility 16 Steerable Guidewire Stainless steel with hydrophilic coating 0.016 175, 205 Shapeable tip The soft tips enable easy shapeability and safe vessel access; available in standard and soft configurations Nipro AquaLiner II Hydrophilic Super-Elastic Nitinol Guidewire Nitinol 0.035, 0.038 150, 180, 260 Angled, straight Engineered to provide optimal pushability, trackability, and kink resistance in challenging anatomy; offers lasting lubricity and tactile feel; our proprietary manufacturing process for the nitinol core results in a kink-resistant guidewire with torque performance that minimizes whip Cordis Aquatrack Hydrophilic Nitinol Guidewire Nitinol 0.035 150, 180, 260 Straight, angled – Asahi Intecc USA, Inc. Asahi Chikai Stainless steel with hydrophilic coating 0.014 200, 300 Straight Designed as workhorse guidewire for neurointerventional procedures; Actone, dual-coil, provides exceptional torque response and durable tip-shape retention; designed with optimum balance between tip flexibility and microcatheter support Asahi Intecc USA, Inc. Asahi Chikai 10 Stainless steel with hydrophilic coating 0.010 200, 300 Straight Designed as workhorse guidewire for neurointerventional procedures; Actone, dual-coil, provides exceptional torque response and durable tip-shape retention; designed with optimum balance between tip flexibility and microcatheter support Asahi Intecc USA, Inc. Asahi Chikai black Stainless steel Actone structure 0.014 200 Round curve/90° angle Neurointervention Asahi Intecc USA, Inc. Asahi Chikai black 18 Stainless steel Actone structure 0.016, 0.018 (reverse taper) 200 Round curve Neurointervention Asahi Intecc USA, Inc. Asahi Chikai V Stainless steel with hydrophilic coating 0.014 165 Straight Designed for super selective embolization; Actone, dual-coil, provides exceptional torque response and durable tip-shape retention for distal branch and multiple vessel embolization Asahi Intecc USA, Inc. Asahi Gaia PV Stainless steel with hydrophilic coating 0.018 200, 300 7.5-gf tip load, preshaped A tapered guidewire with micro cone tip and ACT ONE technology for effective navigation, ease of advancement, and good penetration Asahi Intecc USA, Inc. Asahi Gladius 0.014 Stainless steel with polymer jacket and hydrophilic coating 0.014 200, 300 3-gf tip load, straight A workhorse polymer-jacketed guidewire with ACT ONE technology for superior maneuverability and durability in a broad range of cases Asahi Intecc USA, Inc. Asahi Gladius 0.018 Stainless steel with hydrophilic coating 0.018 200, 300 4-gf tip load, straight A workhorse polymer-jacketed guidewire with ACT ONE technology for superior maneuverability and durability in a broad range of cases Asahi Intecc Co Ltd. Asahi Gladius Mongo 18 PV ES Stainless steel with a polymer jacket and hydrophilic coating 0.018 190, 300 3-gf tip load, straight, preshape A workhorse polymer-jacketed guidewire with high steerability, good support, and the ability to form a narrow loop for crossing and treating stenosed lesions Asahi Intecc Co Ltd. Asahi Gladius Mongo ES Stainless steel with polymer jacket and hydrophilic coating 0.014 190, 300 3-gf tip load, straight, preshape A workhorse polymer-jacketed guidewire with high steerability, good support, and the ability to form a narrow loop for crossing and treating stenosed lesions Asahi Intecc USA, Inc. Asahi Halberd 0.014 Stainless steel with hydrophilic coating 0.014 200, 300 12-gf tip load, straight A specialty guidewire with ACT ONE technology for superior directional control and effective lesion engagement Asahi Intecc USA, Inc. Asahi Halberd 0.018 Stainless steel with hydrophilic coating 0.018 200, 300 12-gf tip load, straight A specialty guide wire with ACT ONE technology for superior directional control and effective lesion engagement Asahi Intecc USA, Inc. Asahi Meister 16 Stainless steel Actone structure 0.016 165, 180 45° angle/round curve/double angle Interventional radiology procedure Asahi Intecc USA, Inc. Asahi Regalia XS 1.0 Stainless steel with a polymer jacket and hydrophilic coating 0.014 180, 300 1-gf tip load, straight A soft polymer guidewire with flexible shaft for trackability in tight lesions and difficult anatomy Asahi Intecc USA, Inc. Astato 30 Stainless steel with hydrophilic coating 0.018 180, 300 30-gf tip load, straight A specialty guidewire with tapered tip for crossing complex lesions with heavy calcification and/or tough fibrous tissue Asahi Intecc USA, Inc. Astato XS 20 Stainless steel with a tapered tip and hydrophilic coating 0.014 180, 300 20-gf tip load, straight A specialty guidewire with tapered tip for crossing complex lesions with heavy calcification and/or tough fibrous tissue Asahi Intecc USA, Inc. Astato XS 40 Stainless steel with tapered tip and hydrophilic coating 0.014 200, 300 40-gf tip load, straight A specialty guidewire with tapered tip and high tip load for crossing complex lesions with heavy calcification and/or tough fibrous tissue Medtronic Avigo .014” Hydrophilic Guidewire Stainless steel 0.014 205 Shapeable tip – Guerbet LLC Axessio Stainless steel with hydrophilic coating 0.018 180 Straight shapeable PTFE and hydrophilic coating with platinum coil tip Guerbet LLC Axessio Stainless steel with hydrophilic coating 0.014 180 Straight shapeable PTFE and hydrophilic coating with platinum coil tip Medcomp Coated Mandrel Guidewires Straight 0.010 60, 80 Platinum coil tip Hydrophilic coating Asahi Intecc Co Ltd. CrossLead 0.035 Nitinol with a polymer jacket and hydrophilic coating 0.035 200, 300 Angled A multipurpose nitinol guide wire with shapeable tip and narrow looping technology for sheath delivery, lesion crossing and device delivery in difficult anatomy and complex lesions Silk Road Medical Enroute 0.014-inch Guidewire Stainless steel with hydrophilic coating 0.014 95 Shapeable, 5-cm radiopaque tip Designed for navigating tortuous short vessel segments with its unique combination of short length, short taper, and a shapeable tip; excellent torque control and device deliverability Boston Scientific Corporation Fathom-14 Guidewire Hybrid stainless steel and nitinol 0.014 200, 300 10 cm with 2-cm shapeable or angled tip Utilizes a unique slotted nitinol hypotube design to balance exceptional torquability with tip softness and proximal support Boston Scientific Corporation Fathom-16 Guidewire Hybrid stainless steel and nitinol 0.016 140, 180, 200, 215 10, 20 cm with 2-cm shapeable or angled tip Utilizes a unique slotted nitinol hypotube design to balance exceptional torquability with tip softness and proximal support Terumo Interventional Systems Glidewire Advantage Hydrophilic Coated Guidewire Nitinol core 0.035 180, 260 Angled: 45°; tip flexibility: 5 cm 25-cm Glidewire hydrophilic distal portion for navigation; stiffer nitinol proximal portion to support device delivery with spiral PTFE coating Terumo Interventional Systems Glidewire Advantage Hydrophilic Coated Guidewire Nitinol core 0.014, 0.018 180, 300 Angled: 45°; tip flexibility: 1 cm 25-cm Glidewire hydrophilic distal portion for navigation; stiffer nitinol proximal portion to support device delivery with spiral PTFE coating; 2-cm gold coil tip Terumo Interventional Systems Glidewire Advantage Track Peripheral Guidewire Stainless steel proximal shaft; nitinol distal tip 0.014, 0.018 180, 300 Angled: 35°, flexibility: 1 cm 25-cm Glidewire hydrophilic distal portion for navigation; stiff stainless steel proximal portion to support device delivery with spiral PTFE coating; 2-cm gold coil tip Terumo Interventional Systems Glidewire Gold Hydrophilic Coated Guidewire Nitinol 0.018 180, 300 45° angle, 70° angle; tip flexibility: 3 cm Terumo Glide technology with 1-mm gold band at tip for enhanced radiopacity Terumo Interventional Systems Glidewire GT Hydrophilic Coated Guidewire Nitinol 0.016, 0.018 180, 200 45° angle, 90° angle, 90°/60° double angle, straight (shapeable); tip flexibility: 25 cm Terumo Glide technology hydrophilic coating with 2-cm gold coil at tip for enhanced radiopacity; flexible distal tip designed for superselectivity Terumo Interventional Systems Glidewire Hydrophilic Coated Guidewire Nitinol 0.018, 0.025, 0.032, 0.035, 0.038 80, 120, 150, 180, 260, 350, 400, 450 Angled, straight, 3 mm J, 1.5 mm “Baby-J”, tip flexibility: 1, 3, 5, 8 cm Terumo Glide technology hydrophilic coating with super elastic nitinol core and polyurethane jacket; standard or stiff shaft Terumo Neuro Headliner Guidewire Guidewire with Terumo Glide technology hydrophilic coating 0.012, 0.016 200 45°, 90° angle; 90°/150° double angle; 1.5-mm J-tip angle; tip flexibility: 20, 35 cm Proprietary Glidewire technology with gold coil at tip for enhanced radiopacity; distal tip specifically engineered for delicate neuro procedures; floppy and standard tip taper available Abbott Hi-Torque Command Nitinol 0.014 190, 300 Shapeable tip Designed for lower limb procedures, available in standard and extra support configurations Abbott Hi-Torque Command 18 Nitinol 0.018 190, 300 Shapeable tip Designed for lower limb procedures; available as ST (short taper, 10 cm nitinol) and LT (long taper, 25 cm nitinol) Balt Hybrid Guidewire Nitinol and stainless steel 0.012 310 Straight, shapeable Designed for stable exchange Balt Hybrid Guidewire Nitinol and stainless steel 0.008 220 Preshaped, double angle Designed for durability and flexibility Balt Hybrid Guidewire Nitinol and stainless steel 0.010 310 Straight, shapeable Designed for stable exchange Balt Hybrid Guidewire Nitinol and stainless steel 0.014 200 Straight, shapeable Designed for durability and flexibility Balt Hybrid Guidewire Nitinol and stainless steel 0.012 200 Straight, shapeable Designed for durability and flexibility Balt Hybrid Guidewire Nitinol and stainless steel 0.012 200 Preshaped, double angle Designed for durability and flexibility Balt Hybrid Guidewire Nitinol and stainless steel 0.007 220 Straight Designed for durability and flexibility Balt Hybrid Guidewire Nitinol and Stainless Steel 0.007 220 Preshaped, double angle Designed for durability and flexibility Balt Hybrid Guidewire Nitinol and stainless steel 0.008 220 Straight, shapeable Designed for durability and flexibility Abbott HydroSteer Nitinol 0.018 150, 180 Angled, straight Hydrophilic coating Abbott HydroSteer Nitinol 0.035, 0.038 150, 180, 260 Angled, straight, J-tip Hydrophilic coating Abbott HydroSteer Guide Wire Nitinol 0.035 150, 180, 260 Straight, angled Nitinol core with polymer jacket Medtronic Mirage .008” Hydrophilic Guidewire Stainless steel 0.012 > 0.008 200 Shapeable tip – Mivi Neuroscience, Inc. Mivi Vi-Radius 014 Stainless steel, hydrophilic coating 0.014 205 Radiopaque platinum tip Platinum tip allows for customized shapeability and deflection through tortuous anatomy Cerenovus Neuroscout 14 Steerable Guidewire Stainless steel with hydrophilic coating 0.014 205, 300 Shapeable tip Specifically designed for excellent tip shaping and shape retention Teleflex PiggyBack Wire Converter Polymer catheter wire converter 0.035 OD 145 Radiopaque marker embedded in distal tip Wire converter with sliding lock securely fastens onto any standard 0.014-inch wire and converts it to a 0.035-inch wire platform BD Interventional Porter Stainless steel 0.014 195, 300 Straight, 3-, 6-, 9-, 12-gauge tip stiffness Hydrophilic guidewire in various levels of tip stiffness, providing excellent trackability, steerability, visibility, and support for delivery of therapeutic devices Cook Medical Roadrunner PC Nitinol core with platinum coils, polyurethane jacket 0.035, 0.038 80, 145, 180, 260 Straight, angled Available in either a standard or stiff shaft configuration and a standard or long-taper configuration Terumo Interventional Systems Runthrough NS Extra Floppy Stainless steel proximal shaft; nitinol distal tip 0.014 180 (can be extended), 300 Floppy Hybrid wire that fuses nitinol and stainless steel for exceptional torque control and tip durability Terumo Interventional Systems Runthrough NS Hypercoat Stainless steel proximal shaft; nitinol distal tip 0.014 180 (can be extended), 300 Straight (shapeable) nitinol Enhanced hydrophilic guidewire for tortuous, distal, tight stenotic complex lesions Terumo Interventional Systems Runthrough NS Izanai Stainless steel proximal shaft; nitinol distal tip 0.014 180 (can be extended), 300 Straight (shapeable) nitinol Enhanced hydrophilic guidewire for complex, tortuous, distal, tight stenotic lesions Boston Scientific Corporation Savion DLVR Stainless steel core, polymer sleeve 0.014 182, 300 Straight (shapeable), angled (shapeable) Guidewire features a 3-cm radiopaque spring coil at the distal end of the core wire that is shapeable; a polymer sleeve, coated with ICE hydrophilic coating, jackets the tapered core wire between the spring coil and the proximal fluorinated polymer coating Boston Scientific Corporation Savion FLX Nitinol core, polymer sleeve 0.014 185, 300 Straight (shapeable), angled (shapeable) Guidewire features a 30-cm radiopaque polymer sleeve, coated with ICE hydrophilic coating, jacketing the nitinol distal core wire; the distal 2 cm is shapeable; the proximal section of the guidewire is PTFE coated Abbott Shepherd Peripheral Guidewires, 12 and 30 gram Stainless steel, hydrophilic with spring coil tip 0.014, 0.018 300 Straight, shapeable – Abbott Shepherd Peripheral Guidewires, 4 and 6 gram Stainless steel, polymer jacket with hydrophilic coating 0.014, 0.018 300 Straight, shapeable – Medtronic Silverspeed .010 Hydrophilic Guidewire Stainless steel 0.010 200 Shapeable tip – Medtronic Silverspeed .014 Hydrophilic Guidewire Stainless steel 0.014 175, 200 Shapeable tip – Merit Medical Systems, Inc. Splash Hydrophilic Coated Guide Wire Nitinol fixed core 0.018, 0.025, 0.035, 0.038 80, 150, 180, 220, 260 Straight, angled, and straight long taper; tip flexibility 5 cm; available in standard and stiff configurations Proprietary nitinol-core wire provides excellent 1:1 torque control; enhanced coating technology provides enduring lubricity for rapid vessel selection Pediavascular Spring Wire Stainless steel 0.030 140 J curve, straight 2-cm floppy tip Stryker Synchro 10 Nitinol 0.010 200, 300 Shapeable Microfabricated nitinol distal hypotube designed for efficient torque transfer Stryker Synchro 14 35-cm Nitinol 0.014 200, 300 Shapeable Microfabricated nitinol distal hypotube designed for efficient torque transfer with a 35-cm distal segment Stryker Synchro 14 45-cm Nitinol 0.014 200, 300 Shapeable Microfabricated nitinol distal hypotube designed for efficient torque transfer with a 45-cm distal segment Stryker Synchro Select Soft Nitinol 0.014 215, 300 Shapeable, preshaped Identical to Synchro Select Standard but with a softer tip and support profile Stryker Synchro Select Standard Nitinol 0.014 215, 300 Shaped, preshaped The trusted Synchro torque, reliability and stability with easier distal navigation and tip shape retention Stryker Synchro Select Support Nitinol 0.014 215, 300 Shaped, preshaped Identical to Synchro Select Standard with a more supportive profile Stryker Synchro2 Soft Nitinol 0.014 200, 300 Shapeable, preshaped Identical to Synchro2 Standard but with a softer tip and support profile Stryker Synchro2 Standard Nitinol 0.014 200, 300 Shapeable, preshaped Designed for torque control; intended for reliable stability and flexibility Stryker Synchro2 Support Nitinol 0.014 215, 300 Shapeable, preshaped Identical to Synchro2 Standard with a more supportive profile Stryker Transend 14 EX Stainless steel 0.014 182 Shapeable Scitanium alloy core wire construction enhances torque transmission and distal support Stryker Transend 14 Soft Tip Stainless steel 0.014 205 Shapeable Identical to the Transend EX Standard but engineered with a softer tip Stryker Transend 300 Extra Support Stainless steel 0.014 300 Shapeable 300-cm exchange guidewire designed for proximal support with a soft platinum coil tip for superb radiopacity and atraumatic tip Stryker Transend 300 Floppy Stainless steel 0.014 300 Shapeable An exchange wire identical to the Transend 300 ES but with a floppier distal segment Boston Scientific Corporation Transend-14 Steerable Guidewire Hydrophilic coating with scitanium core 0.014 135, 165, 190 2-cm shapeable tip Product features hydrophilic coating and good torque response Boston Scientific Corporation Transend-18 Steerable Guidewire Hydrophilic coating with scitanium core 0.018 135, 165 2-cm shapeable tip Product features hydrophilic coating and good torque response Terumo Neuro Traxcess 7 Mini Hydrophilic guidewire 0.007 210 Soft 0.007-inch tip tapers to 0.014-inch guidewire body Terumo Neuro Traxcess Docking Wire Docking wire 0.014 115 – Compatible with Traxcess guidewire Terumo Neuro Traxcess Guidewire Hybrid nitinol/stainless steel construction with hydrophilic coating 0.012; 0.014 (proximal) 200 Soft, atraumatic tip; shapeable 1.4-cm tip length; straight with 0.012-inch distal diameter to access small vessels – Asahi Intecc USA, Inc. Treasure 12 Stainless steel with hydrophilic coating 0.018 180, 300 12-gf tip load, straight A specialty guidewire for controlled drilling when targeting highly stenosed, calcified lesions Asahi Intecc USA, Inc. Treasure Floppy 0.018 Stainless steel with hydrophilic coating 0.018 190, 300 4-gf tip load, straight Workhorse guidewire for nontotally occluded lesions Merit Medical Systems, Inc. True Form Reshapable Guide Wire Stainless steel 0.014 145, 165, 180 Straight, angled Reshapable tip Cook Medical Uniglide Nitinol core, polyurethane jacket 0.018, 0.035 80, 150, 180, 260, 320 Straight, angled Available in either a standard or stiff shaft configuration Boston Scientific Corporation V-14 ControlWire Guidewire Scitanium stainless steel core, polymer sleeve 0.014 182, 300 Straight, angled (shapeable) Distal radiopaque section (distal 2 cm); single-piece core with torque jacket for 1:1 torque control; shapeable tip intended to facilitate accurate placement; proximal PTFE jacket intended to provide firm support and low friction surface Boston Scientific Corporation V-18 ControlWire Steerable Guidewire Scitanium stainless steel core, polymer sleeve 0.018 110, 150, 200, 300 Straight (shapeable) Hydrophilic performance and torque control designed for distal, peripheral access and contralateral approaches; single-piece core with torque jacket for 1:1 torque control; robust shapeable 3-cm tip intended to facilitate accurate placement; proximal PTFE jacket intended to provide firm support and low friction surface US Endovascular Victoria Super elastic nitinol 0.035 145, 180, 260 Straight/angled Super elastic nitinol core/proprietary hydrophilic coating Boston Scientific Corporation Victory Guidewire Stainless steel core, polymer sleeve 0.014, 0.018 195, 300 Straight (shapeable) 12-g, 18-g, 25-g, and 30-g tip loads designed to cross highly resistant lesions; torque control designed for distal, peripheral access Medtronic X-Celerator Hydrophilic Exchange Guidewire Stainless steel 0.010, 0.014 300, 350 Shapeable tip – Medtronic X-Pedion .010 Hydrophilic Guidewires Stainless steel 0.012 > 0.010 200 Shapeable tip – Medtronic X-Pedion .014 Hydrophilic Guidewires Stainless steel 0.014 200 Shapeable tip –