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CAS 120-73-0 vs. CAS 122-40-6: Key Differences Explained

Oct. 14, 2026

When comparing various chemical compounds, it’s essential to understand their unique properties and applications. In the realm of chemical identifiers, CAS numbers help in clearly differentiating substances. Here, we will explore CAS 120-73-0 and CAS 122-40-6, detailing their key differences.

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What are CAS 120-73-0 and CAS 122-40-6?

CAS 120-73-0 is primarily known as 4-Amino-2-methylphenol, while CAS 122-40-6 is recognized as 5-Amino-3-methylphenol. Both compounds belong to the category of aromatic amines and are used in various applications, particularly in the production of dyes and as API raw materials in pharmaceuticals.

1. What are the chemical structures of CAS 120-73-0 and CAS 122-40-6?

The chemical structures differentiate these two compounds:

  • CAC 120-73-0 (4-Amino-2-methylphenol): It has an amine group (-NH2) located at the para position relative to a hydroxyl group (-OH) on the benzene ring, making it suitable for dye synthesis.
  • CAS 122-40-6 (5-Amino-3-methylphenol): In this compound, the amine group is situated at the meta position adjacent to the hydroxyl group, which alters its reactivity and application range.

2. What are the primary applications of each compound?

Both CAS 120-73-0 and CAS 122-40-6 serve critical roles in various industries:

  • CAS 120-73-0: This compound is often utilized in the preparation of dyes, pigments, and other chemical intermediates, particularly in the textile industry. Its function as an API raw material makes it valuable in pharmaceutical formulations.
  • CAS 122-40-6: Similarly, this compound is also found in dye manufacturing. It serves as a precursor for pharmaceuticals, contributing to the creation of other necessary compounds in drug development.

3. How do their physical properties differ?

Understanding the physical properties is crucial for their handling and usage:

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  • CAS 120-73-0: This compound typically appears as a light gray to white crystalline powder. It has a melting point of about 95-97°C and is soluble in water, making it easy to incorporate into various chemical processes.
  • CAS 122-40-6: On the other hand, CAS 122-40-6 also presents as a crystalline substance but has a melting point around 138-141°C. Its solubility in water is moderate, which might affect its practical applications in some scenarios.

4. Are there any safety concerns associated with CAS 120-73-0 and CAS 122-40-6?

Safety is a vital aspect when handling chemicals:

  • CAS 120-73-0: This compound is considered to have moderate toxicity. Proper safety measures need to be taken to avoid skin and eye irritation. Inhalation or ingestion should be strictly avoided.
  • CAS 122-40-6: CAS 122-40-6 is similarly classified with moderate toxicity, requiring careful handling. It can also cause irritation upon contact and must be stored safely according to material safety data sheets (MSDS).

5. How do the costs of CAS 120-73-0 and CAS 122-40-6 compare?

The pricing of chemical compounds can vary based on several factors, including supply, demand, and production costs:

  • CAS 120-73-0: Generally, you can expect this compound to be slightly less expensive due to a more extensive availability in the market and established applications.
  • CAS 122-40-6: This compound may be priced higher due to its more specialized applications in certain pharmaceuticals, affecting its market dynamics.

6. How to choose between CAS 120-73-0 and CAS 122-40-6 for specific applications?

Selecting the right compound depends on your project needs:

  • If your application requires a compound with a lower melting point and higher water solubility, CAS 120-73-0 would be more suitable.
  • In contrast, if you need a compound for specific pharmaceutical applications with a moderate melting point and unique reactivity, CAS 122-40-6 would be the better choice.

Conclusion

In summary, both CAS 120-73-0 and CAS 122-40-6 play significant roles in the chemical industry, particularly in the dye and pharmaceutical sectors. Understanding their differences in structure, applications, physical properties, safety concerns, and cost can assist businesses and researchers in making informed decisions regarding their use.

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