Prof. Dr. Erdem Yeşilada, Head of Yeditepe University Pharmacognosy and Phytotherapy Department, explained:

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It has been experimentally proven that olive has anti-inflammatory, blood sugar lowering, blood pressure lowering, atherosclerosis preventing, blood lipid level lowering, bone loss repairing, anti-microbial, antioxidant, and anticancer properties, and many other effects.

What makes olive so effective is its rich polyphenolic content, hydroxytyrosol, oleuropein, oleocanthal, etc. The strong antioxidant effect of green tea is always mentioned. However, hydroxytyrosol has an antioxidant effect that is 10 times stronger than green tea. However, because their taste is bitter, when we put the olive fruits in water, we also lose these beneficial substances in the black-colored water that comes out. Purification of olive oil also means the removal of these components. The olive leaves that are pruned and thrown away are the most important source of polyphenolic compounds.

Applied to Overweight Individuals

In a study published in , it was reported that olive leaf extract is effective in sugar metabolism in type-2 diabetics and reduces the level of glycosylated hemoglobin (HbA1c) after 14 weeks of administration.

In a clinical study carried out in , the effect of olive leaf on 'insulin resistance', which is one of the main factors of obesity in humans, was investigated. In the measurements, it was observed that olive leaf extract improves insulin sensitivity by 15-20 percent. This value is reportedly the same as some known diabetes medications…

In experiments on the mode of action, it was suggested that olive leaf extract exerts its effect by stimulating the secretion of factors that regulate insulin sensitivity (IGFBP-2) and prevent excess insulin secretion (IGFBP-1).

How Safe Is Olive Leaf Extract?

No adverse changes were observed in the liver and kidney values of the subjects with the administration of the extract. In this regard, the olive leaf extract is reported to be safe.

Olive Leaf Tea Is More Beneficial

As for the residence time in the body, oleuropein was found to reach its highest blood level in an average of 80 minutes after oral administration and is excreted from the body in 240 minutes. However, it was observed that the olive leaf extract preparations in liquid form are absorbed quite quickly (23 minutes), while the absorption time in tablet form reaches 80-90 minutes.

Another interesting observation is that the hepatic metabolite of hydroxytyrosol (hydroxytyrosol glucuronide) has a five times higher antioxidant effect.

In this case, drinking tea of appropriate quality containing olive leaves before meals or taking capsules containing olive leaf extract should be considered as one of the effective measures to be taken against insulin resistance.

Olive Leaf Extract is most often used for Immunity & Infectious Disease. The Examine Database covers High Blood Pressure, High Cholesterol, and 3 other conditions and goals.

Olive Leaf Extract

Olive leaf extract comes from the leaves of olive plants and is distinct from olive oil. Rich in phenolics such as oleuropein, this extract offers potential cardiovascular benefits. It may help reduce blood pressure and improve blood lipids as well as reduce inflammation.

Olive Leaf Extract is most often used for Immunity & Infectious Disease. The Examine Database covers High Blood Pressure, High Cholesterol, and 3 other conditions and goals.

Last Updated:September 25,

What is olive leaf extract?

Olive leaf extract is a concentrated supplement derived from the leaves of olive trees, unlike olive oil, which is made from the fruit. Although olive oil is mainly used for cooking, olive leaf extract serves as a dietary supplement.

What are olive leaf extract’s main benefits?

Olive leaf extract is purported to benefit cardiovascular and metabolic health, and some studies suggest that it may reduce blood pressure in people with prehypertension and hypertension. However, the overall quality of the research is low, and more recent studies have found no significant effects, which indicates that any potential benefits should be viewed with caution.

What are olive leaf extract’s main drawbacks?

Olive leaf extract is generally well tolerated, but some people have reported side effects such as stomachache, headache, and acne. Further research is necessary to fully understand its potential drawbacks.

How does olive leaf extract work?

Olive leaf extract primarily works through its polyphenols, particularly oleuropein, which are believed to provide various benefits, including antioxidant, antihypertensive, antidiabetic, and anti-inflammatory effects. Most of these benefits have been observed in in vitro and animal studies.

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What are other names for Olive Leaf Extract ?

Note that Olive Leaf Extract is also known as:

• Olea europaea L
• Olive leaf polyphenols

Olive Leaf Extract should not be confused with:

• Olive oil
• Olive oil polyphenols

Research FeedRead all studies

In this 24-week randomized controlled trial in 31 participants with type 2 diabetes, olive leaf extract did not improve HbA1c.

Frequently asked questions

Olive leaf extract is a concentrated supplement derived from the leaves of olive trees, unlike olive oil, which is made from the fruit. Although olive oil is mainly used for cooking, olive leaf extract serves as a dietary supplement.

Olive leaf extract is derived from the leaves of olive trees. It is distinct from olive oil, which is harvested directly from the olive fruit. While olive oil is used primarily for cooking and as a food ingredient, olive leaf extract is processed into a concentrated form as a supplement.

The main bioactive compound in olive leaf extract is oleuropein, which contributes to the distinct taste of olive oil. Its content decreases in black olives as they mature, likely due to increased esterase enzyme activity that metabolizes oleuropein into other compounds.

The main bioactive in olive leaf extract appears to be oleuropein, which is a highly pungent compound claimed to be the cause of olive oil's distinct taste.[9] Black olives tend to have their oleuropein content decline towards maturation,[10] with some species having no detectable oleuropein at full blackening.[11] This is thought to be related to an increased level of esterase enzyme activity which metabolizes oleuropein into other compounds.[12]

Olive leaf extract is purported to benefit cardiovascular and metabolic health, and some studies suggest that it may reduce blood pressure in people with prehypertension and hypertension. However, the overall quality of the research is low, and more recent studies have found no significant effects, which indicates that any potential benefits should be viewed with caution.

Olive leaf extract’s main purported benefit is its effect on cardiovascular health and metabolic health. Some research has found that olive leaf extract reduced blood pressure in people with prehypertension and hypertension[1] and in the general adult population.[3] However, the quality of the research was quite low. More recent research found no effect on blood pressure or other markers of cardiometabolic health.[2] Given the low quality and limited amount of research, olive leaf extract might be beneficial for cardiovascular health, but these findings should be interpreted with caution.

Olive leaf has a long history of traditional medicinal use in the Mediterranean and parts of Africa, where it has been used to treat conditions such as diabetes, high blood pressure, and atherosclerosis. Additionally, it has been used as a diuretic, emollient, fever reducer, and a treatment for urinary infections and headaches.

Olive leaf has a history of use in traditional medicine, particularly in the Mediterranean, including Spain, Italy, France, Greece, Israel, Morocco, and Turkey. Its use also extends to Africa, where the Sotho, Xhosa, and Zulu tribes also use olive leaf for medicinal purposes.[7]

Traditionally, olive leaf has been used to treat diabetes, high blood pressure, and atherosclerosis. Some other traditional uses for olive leaf include use as a diuretic, emollient, fever reducer, treatment for urinary and bladder infections, and as a treatment for headaches.[8][7]

Olive leaf extract is generally well tolerated, but some people have reported side effects such as stomachache, headache, and acne. Further research is necessary to fully understand its potential drawbacks.

Clinical trials in humans have found olive leaf extract to be generally well tolerated.[3] There are some reports of stomachache, headache, and acne after supplementation.[4] However, more research is needed to fully understand any potential drawbacks of olive leaf extract supplementation.

Olive leaf extract primarily works through its polyphenols, particularly oleuropein, which are believed to provide various benefits, including antioxidant, antihypertensive, antidiabetic, and anti-inflammatory effects. Most of these benefits have been observed in in vitro and animal studies.

Olive leaf extract works primarily through its polyphenols, such as oleuropein. These substances are believed to have numerous benefits, such as antioxidant, antihypertensive, antidiabetic, and anti-inflammatory effects.[5][6] However, a majority of these benefits come from in vitro and animal studies.

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Examine Database References

1. Liver Enzymes - Susalit E, Agus N, Effendi I, Tjandrawinata RR, Nofiarny D, Perrinjaquet-Moccetti T, Verbruggen MOlive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with CaptoprilPhytomedicine .( Feb 15 )
2. Blood Pressure - Perrinjaquet-Moccetti T, Busjahn A, Schmidlin C, Schmidt A, Bradl B, Aydogan CFood supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twinsPhytother Res .( Sep )
3. Total cholesterol - de Bock M, Derraik JG, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WSOlive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover TrialPLoS One .( )
4. HbA1c - Wainstein J, Ganz T, Boaz M, Bar Dayan Y, Dolev E, Kerem Z, Madar ZOlive leaf extract as a hypoglycemic agent in both human diabetic subjects and in ratsJ Med Food .( Jul )
5. Blood Pressure - Álvares AA, Garcêz A, Silva LT, Averbuch N, Garavaglia JOlive leaf extract effect on cardiometabolic risk factors: a systematic review and meta-analysis of randomized clinical trials.Nutr Rev .( Jan 29 )